|Exam Name||:||Replication Solutions for the HP StorageWorks EVA|
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significant organizations generate an almost unfathomable amount of information. whereas this creates extraordinary possibility for answer suppliers to present backup and catastrophe recuperation capabilities for these valued clientele, it also introduces an issue – backing up, replicating and securing these massive records shops. it's extremely inefficient and costly.
usual options lower back up all of a customers’ data at set intervals, introducing redundancy. Sepaton’s new DeltaRemote application, attainable may 30, leverages the supplier’s DeltaStor deduplication utility to get rid of redundancy in valued clientele’ statistics before it’s backed up, says Steve Bagby, senior director of product planning and engineering for Sepaton.
with the aid of replicating handiest important changes to a backup or disaster restoration site, the utility makes more efficient use of storage means and shrinks backup windows through cutting back the volume of information that’s backed up, he says. truly, Bagby says, a solution that includes deduplication can decrease bandwidth requirements by means of as plenty as 97 %, and tremendously accelerate the replication and migration of huge business purchasers’ statistics to faraway websites, making backup much extra efficient and less expensive.
furthermore, on account that backups are accomplished much greater without delay, there’s a lessen chance for statistics loss or corruption during the backup process.
"DeltaRemote lets our answer provider partners ship colossal information packets over a LAN connection and replicate that data off web site," Bagby says. "through the use of deduplication, bandwidth utilization is extended and simplest new, pleasing information is replicated as an alternative of transporting redundant statistics, which is inefficient," he says.
Bagby says answer suppliers can present the brand new utility equipment to their large enterprise purchasers that deserve to replicate facts from a primary information core to a catastrophe restoration site, in addition to customers that are gigantic ample to need move-replication for catastrophe restoration amongst assorted websites.
He provides that Sepaton will make the solution accessible throughout the providers’ personal network of answer providers as well as partnering with storage and information center heavyweights like Hewlett-Packard to carry the solution through their channel.on the grounds that the answer can pretty much dispose of tape dealing with, the skills for tape screw ups, records loss and theft and facts corruption are slashed dramatically, he says.
DeltaRemote gives internet-based access into the total solution, together with the replication capabilities, Bagby says. The answer also contains load-balancing aspects within the adventure of a storage node failure to at once get agencies up and operating within the event of a disaster.
moreover, answer suppliers can use reporting features to bring as much as 90 days of bandwidth fashion analysis to shoppers, helping them superior take into account utilization necessities.
"This feature can also display customers the place bottlenecks are occurring, and improved analyze how they could cut back those, or, if necessary, when to update their LAN/WAN," Bagby says.
IRVINE, CA--(Marketwired - Aug 13, 2013) - imaginative and prescient solutions, Inc., a number one company of information insurance policy and migration software and functions, nowadays announced that its flagship product, Double-Take Availability, will now be provided for the HP StoreEasy Storage portfolio. together, these items provide clients the records coverage equipment that they should ensure excessive records availability and meet the "always-on" quintessential of modern day marketplace.
Double-Take Availability is used with the aid of lots of businesses around the globe to give protection to hundreds of thousands of actual and digital servers, with precise-time replication for high availability (HA), catastrophe recovery (DR) and far flung office/branch office (ROBO) operations. Its the rest-to-anything else replication capabilities mean agencies with heterogeneous environments (infrastructure that includes physical servers, virtualized servers and/or the cloud) can with ease circulation data and applications between these very different applied sciences, in addition to deliver failover of servers in an emergency, in minutes in place of hours and even days.
"due to the internet, lots of modern organizations operate 24x7," pointed out Doug Piper, VP of Product strategy at vision solutions. "income, inventory tiers, productivity and different essential facts are being collected continuous. All of these techniques are impacted when catastrophe strikes. adding the mighty facts replication capabilities of our Double-Take Availability to HP StoreEasy Storage offers companies of all sizes an incredibly potent and finished yet most economical skill of ensuring their organizations are prepared for any catastrophe -- herbal or man-made."
different points of Double-Take Availability for HP StoreEasy Storage include:
"Interrupted entry to file records can drain productivity and choke a growing to be business," noted Craig Nunes, vice president of advertising and marketing, Storage, HP. "HP StoreEasy Storage with Double-Take Availability offers cozy file storage and excessive availability for groups searching for 24x7 sanctuary from the sudden. enterprise continuity has by no means been easier or greater low in cost."
About imaginative and prescient options (visionsolutions.com)
imaginative and prescient solutions® is the premier issuer of cloud insurance policy and healing, high availability, disaster recovery, migration and go-platform statistics sharing solutions for IBM vigor systems, home windows, Linux, AIX and cloud computing. imaginative and prescient options' Double-Take®, iTERA™ and MIMIX® options make it effortless for groups to undertake cloud-primarily based disaster recuperation innovations, perform close-zero downtime migrations with out risk, share facts in precise-time throughout platforms and circulate, give protection to and repair statistics, applications and operating techniques of any form on any combination of actual, digital or cloud servers. And, no longer best do our products dispose of downtime, they continue to adapt alongside the most reducing-area know-how available on the market.
For protein expression in human cells, 293T cells have been transfected with indicated plasmid the usage of XtremeGENE HP transfection reagent (Roche) in accordance with the manufacturer’s protocol. 5 microgram of plasmid DNA and 15 µl of XtremeGENE HP were used for 293T cells (~1 × 106 cells) on 6 cm-dish. Twenty-four hours after transfection, the media became replaced by means of DMEM (Gibco) containing 10% FBS. Seventy-two hours after transfection, cells have been harvested via mobilephone scraper and subjected to immunoprecipitation.
For siRNA transfection, U2OS cells had been transfected with siRNA (Supplementary desk 1) the use of RNAiMAX transfection reagent (Invitrogen) in keeping with the brand’s instruction. 4 microliter of 50 µM duplex RNAs and 10 µl of RNAiMAX reagent have been used for U2OS cells (~0.7 × 106 cells) on 6 cm-dish. Seventy-two hours after siRNA transfection, cells were handled with a hundred nM camptothecin (CPT; Wako) and subjected to immunofluorescence. Depletions of SWSAP1 and FIGNL1 have been tested by using depletion of FLAG-SWSAP1 and Myc-FIGNL1, respectively (Supplementary Fig. second, e). Protein expression of siRNA-resistant SWSAP1 mutants in siRNA-transfected cells had been analyzed through western blot (Supplementary Fig. 2f, g).Immunoprecipitation (IP)
After washing with PBS, cells had been resuspended in 500 μl of benzonase buffer (20 mM Tris-HCl at pH 7.5, forty mM NaCl, 2 mM MgCl2, 0.5% NP-40, 50 U/ml benzonase [Millipore], 1× Protease inhibitor [Roche], 1× phosphatase inhibitor [Roche]), incubated for 10 min at 4 °C and cleared by centrifugation at 15,000 × g for 10min42. the consequent extracts (WCE) have been diluted with via including 2 × WCE volume of No-salt IP buffer (25 mM Tris-HCl at pH 7.5, 1.5 mM DTT, 15% Glycerol, 1× Protease inhibitor, 1× phosphatase inhibitor). Twelve microliter of EZview crimson anti-Myc affinity Gel (Sigma) were brought to 300 µl of diluted extracts and incubated for 2 h at four °C. After incubation, beads were washed 3 times with IP buffer (25 mM Tris-HCl at pH 7.5, 150 mM NaCl, 1.5 mM DTT, 10% Glycerol, 0.25% NP-forty, 1× Protease inhibitor, 1× phosphatase inhibitor) and proteins had been eluted with 50 μl of SDS sample buffer.Antibodies
Anti-RAD51 (1:one hundred Santa Cruz, sc8364), anti-DMC1 (1:50 Santa Cruz, sc22768), anti-SYCP3 (1:500 abcam, ab97672), anti-γH2AX (1:500 Millipore, 05–636) antibodies had been used for immunofluorescence staining of spermatocyte unfold. Anti-RAD51 (1:500 Millipore, ABE257) and anti-γH2AX (1:one thousand Millipore, 05–636) antibodies have been used for immunofluorescence staining of U2OS cells. Anti-FLAG (1:3000 Wako 012-22384) and anti-Myc (1:3000 Nacalai 04362-34) antibodies have been purchased from Wako and Nacalai, respectively. For pulldown assay, anti-FIGNL1 (1:500 abcam, ab173685) and anit-SWSAP1 (1:500 Thermo, PA5-25460) had been used.Western blot
IP and WCE samples had been separated by 12% SDS-polyacrylamide gels and transferred onto a PVDF membrane (Millipore). The blots have been blocked with 5% milk in TBST for 30 min and incubated with simple antibody in a single day and secondary antibody for 30 min. Proteins had been detected by means of alkaline phosphatase kits (Nacalai). Uncropped photos for every western blots are proven in Supplementary Fig. 6.Clonogenic survival
SV40-immortalized mouse fibroblasts prepared as described below have been seeded on 10 cm-dishes. After 8 h, cells have been handled with indicated attention of camptothecin (Wako) for 22 h and mitomycin C (Nacalai), at all times. Ten days after medicine, cells had been stained in four% crystal violet (Sigma). The number of colonies become counted.Immunofluorescence staining
Cells were cultured on coverslips within the presence or absence of one hundred nM camptothecin for 22 h. Cells were permeabilized with CSK buffer (10 mM PIPES at pH 6.eight, one hundred mM NaCl, 300 mM Sucrose, three mM MgCl2, 1 mM EGTA, 0.5% Triton X-one hundred, 1× protease inhibitor cocktail, 1× phosphatase inhibitor) for five min on ice and fixed with 2% PFA (Sigma) for 15 min at room temperature. The coverslips have been blocked in TBST containing three% BSA. in consequence, coverslips were incubated with fundamental antibodies in TBST containing 3% BSA for overnight, washed three times with TBST and secondary antibodies for 1 h. After washing with TBST, the coverslips were installed with Vectashield media (Vector Laboratories).
Stained spreads were observed the usage of an epi-fluorescence microscope (BX51; Olympus) with a 60 × goal (NA1.three). photographs had been captured by using CCD camera (CoolSNAP; Roper). Mouse spermatocyte spreads were observed the use of a laptop-assisted fluorescence microscope gadget (DeltaVision; utilized Precision). The goal lens become an oil immersion lens (100×; NA, 1.35). graphic deconvolution became performed using a picture workstation (SoftWorks; utilized Precision), and afterwards processed using iVision (Sillicon), and Photoshop (Adobe) utility equipment.Spermatocyte spreads
Testis become incubated in 2 ml testis isolation medium (104 mM NaCl, 45 mM KCl, 1.2 mM MgSO4, 0.6 mM KH2PO4, 0.1% glucose, 6 mM sodium lactate, 1 mM sodium pyruvate) containing 2 mg-ml-1 collagenase (Worthington) at 32 °C for 55 min43. as a result, testis became treated with 0.7 mg ml-1 trypsin (Sigma) and four µg-ml-1 DNaseI (Roche) at 32 °C for 15 min. The reaction changed into stopped by including 20 mg-ml-1 trypsin inhibitor in testis isolation medium (Sigma). the consequent suspension changed into filtered through a 70-µm mobilephone strainer (Corning). After washing with testis isolation medium, cells have been resuspended in 0.1 M sucrose and utilized to a spot containing 1% PFA on glass slide. The slides had been dried below moist situation for two.5 h and dry circumstance for 1 h. After rinsing with DRIWEL (FujiFilm), slides have been stored at −eighty °C.Protein purification
FIGNL1ΔN (N-terminal 284aa deletion) sequence was inserted into EcoRI web site of pGEX-2T (GE Healtcare). FIGNL1ΔN-EE (F295E, A298E) and FIGNL1ΔN-KR (K447R) were generated by PCR-mediated site-directed mutagenesis. BL21 (DE3) became changed with pGEX-2T-FIGNL1ΔN. Protein expression became brought on by including IPTG to ultimate 0.2 mM for 3 h at 37 °C. cell pellets were resuspended in buffer-A containing 50 mM Tris-HCl (pH 7.5), 150 mM NaCl, disrupted through sonication and cleared by centrifugation. Lysates had been filtered and utilized to GSTrap column (GE Healthcare) on an ÄKTA Pure equipment. Proteins had been eluted with a gradient of glutathione. GST-FIGNL1ΔN containing fractions were incubated with thrombin (GE Healthcare) to eradicate GST tag at room temperature. After 16 h incubation, the fractions were applied to HiTrap SP (GE Healthcare). Proteins have been eluted with a gradient of NaCl. FIGNL1ΔN-containing fractions have been focused the usage of Amicon ultra 30 k centrifugal filter unit (Millipore). Purified proteins had been analyzed by way of SDS-page with Coomassie staining (Supplementary Fig. S3b, d). FIGNL1ΔN-EE (F295E, A298E) and FIGNL1ΔN-KR (K447R) proteins were purified as wild-classification FIGNL1ΔN, and showed identical behaviors during the purification to the wild-classification protein.
For pulldown assay, human SWSAP1 and SWS1 sequences have been inserted into NdeI/SalI site of pET28a expression vector (Novagen). BL21 (DE3) codon plus stress became converted with the pET28a–SWSAP1–SWS1 plasmid and cultured at 37 °C for the expression of His6–SWSAP1–SWS1 complicated. Protein expression became triggered by means of adding IPTG to a last attention of 0.2 mM for sixteen h at 18 °C. Bacterial pellets in had been sonicated and cleared by using centrifugation. Resultant bacterial lysates were applied to Ni-NTA (Qiagen). His-tagged SWSAP1 and SWS1 complicated become eluted with a gradient of imidazole in buffer-A. Purified proteins have been analyzed with the aid of SDS-web page with Coomassie staining.
For RAD51 disassembly assay, human SWSAP1 sequence was inserted into SmaI website of pGEX-2T vector, leading to pGEX-2T–SWSAP1. BL21 (DE3) codon plus strain become transformed with the pGEX-2T–SWSAP1 plasmid. A colony was incubated in LB media at 37 °C in a single day. The lifestyle became transferred to significant LB lifestyle and incubated for two h at 37 °C. Protein expression became brought on by means of addition IPTG to final 0.2 mM for three h. Bacterial pellets were resuspended in buffer-A and sonicated. Lysates have been filtered and utilized to GSTrap column on an ÄKTA Pure device. GST-SWSAP1 turned into eluted with glutathione containing buffer-A and treated with thrombin overnight to eliminate GST tag. After thrombin medication, SWSAP1 protein changed into purified with HiTrap Q (GE Healthcare) with a gradient of NaCl and centred by means of Amicon extremely 10 okay centrifugal filter unit (Millipore). Protein attention changed into determined by Bradford formulation (BioRad) using BSA as a common.GST pulldown assay
GST pulldown become carried out using MagneGST pulldown gadget (Promega) according to the company’s guide. Extracts of bacteria expressing GST or GST–FIGNL1ΔN were organized as proven in Protein purification and incubated with forty µl GST beads for 1.5 h at four °C. Beads were washed with a buffer containing 50 mM Tris-HCl (pH 7.5) and 150 mM NaCl and incubated with 10 µl of 10 µM purified SWSAP1–SWS1 complex. After 1.5 h incubation, beads were washed three times with buffer containing 50 mM Tris-HCl (pH 7.5), one hundred fifty mM NaCl, 5% Glycerol, 10 mM DTT, and nil.5% Triton X-one hundred. sure proteins have been eluted with 50 µl of 10 mM glutathione in the equal buffer. Eluted samples and inputs have been subjected to western blotting.RAD51 disassembly assay from ssDNA immobilized on magnetic beads
5′-biotinylated 83nt ssDNA become immobilized on Dynabeads MyOne Streptavidin (Invitrogen) within the presence of 0.5 mg-ml-1 BSA and nil.015% NP-forty. In Supplementary Fig. 5b, 5′-biotinylated 43nt, 83nt, and 153nt ssDNA had been used. Beads have been washed once and incubated with 0.four µM RAD51 in 25 µl of the buffer containing eighty mM HEPES at pH 7.5, 20 mM Mg(OAc)2, sixteen mM ATP, 4 mM DTT, a hundred mM NaCl, 0.04% NP-40 at 22 °C. After 20 min incubation, the beads have been collected and incubated with purified FIGNL1ΔN, FIGNL1ΔN-EE or FIGNL1ΔN-KR in 20 µl of a buffer containing 20 mM HEPES at pH 7.5, 50 mM Mg(OAc)2, four mM ATP, 1 mM DTT, 25 mM NaCl, 0.1% NP-forty, 5% Glycerol, 15 µM ϕX174 Virion (NEB) for 20 min at 22 °C. In Supplementary Fig. 5a, 5 mM CaCl2 changed into used instead of Mg(OAc)2. Supernatants were reserved as unbound fractions. Beads had been washed as soon as with TE with one hundred mM KCl, 0.01% NP-forty and the ssDNA-bound proteins had been eluted with 20 µl SDS pattern buffer. ssDNA-bound and unbound fractions were resolved on SuperSep Ace 12.5% gel (Wako) and stained with CBB or InstantBlue (Expedeon). Bands have been quantified the use of ImageQuantTL (GE Healthcare). Percentages of RAD51 within the supernatant and ssDNA-sure fractions have been calculated through dividing measured values of RAD51 bands in the supernatant or ssDNA-bound fractions by way of complete values (Supernatant + ssDNA-sure).measurement of ATPase activity
Reactions have been carried out in buffer containing 25 mM Tris-HCl (pH 7.5), a hundred ng µl-1 BSA, 1 mM DTT, 10 mM MgCl2, 2 mM ATP and 1 µCi [γ-32P]ATP at 37 °C. After incubation, the reactions had been stopped through the addition of 10 mM EDTA. The reaction items had been separated by TLC PEI Cellulose (Millipore) and analyzed with a FLA9000 (GE Healthcare).Metaphase spreads
Metaphase unfold had been performed in keeping with a common protocol44,forty five. briefly, after ~ninety h of siRNA transfection of U2OS cells, cells had been treated with 0.2 µg ml−1 colcemid (Gibco) for 2 h at 37 °C, washed with PBS and trypsinized. 5 ml of 75 mM KCl turned into brought to cells resuspended in ultimate PBS. After 20 min incubation, fixation solution (MeOH:AcOH; three:1) changed into introduced dropwise. After 5 min incubation, cells have been accumulated by centrifugation, washed with fixation answer and incubated in fixation answer in a single day. The cellphone suspension became dropped on glass slide and air-dried. Slides had been stained with four% Giemsa answer (Merck) for forty five min and mounted with 50% glycerol. The chromosome graphic become captured using a microscope (BX51; Olympus, Japan) with a one hundred × goal (NA1.three). photographs had been captured through CCD digicam (SPOT Pursuit; SPOT imaging), and afterwards processed the use of SPOT photograph application (SPOT imaging), and Photoshop (Adobe) application tools.Animal care
The care and use of mice in this analyze were performed based on the guiding principle for relevant conduct of animal experiments (Society Council of Japan). These strategies were accredited with the aid of Institutional Animal Care committee in Institute for Protein analysis, Osaka institution (approval id; 25-03-0).Animals
Swsap1 focused on vector containing β-geo cassette, loxP website, exon2 and loxP site, changed into received from KOMP. The targeting vector became used to substitute exon2 of mouse Swsap1 gene. the consequent ES cells were injected into ICR host blastocysts and implanted into pseudopregnant feminine mice. acquired chimeric mice were bred to C57BL/6 mice. The heterozygous mice had been mated with CAG-Cre mice to delete exon2. the ensuing Swsap1+/− mice had been bred to acquire Swsap1−/− mice. Genotypes have been demonstrated via PCR with the following primers: mSWSAP1-check-f(ATGGCGGAGGCGCTGAGGCGGGTGCTGAA), mSWSAP1-2step-f (CGGTTTCCATATGGGGATTGGTGGCGACGA), mSWSAP1-check-r2(TGCCTTATTTCCTGATCCAGGCTAGCTGTC).Histology
For histology of testes, samples were fix in a single ml of Bouin solution (Wako 023-17361) overnight and in 10% buffered formaldehyde in a single day. For histology of ovaries, samples had been fixed in a single ml of 10% buffered formaldehyde overnight. After fixation, samples have been embedded, sectioned and stained with hematoxylin–eosin. Stained samples had been analyzed by using NHSL (New Histo Science Laboratory).cellphone line derivation
Mouse ear fibroblasts were derived the usage of common protocol46. in short, small pieces of ear had been handled with protease solution containing collagenase (Roche) and Dispase (Roche) for forty five min at 37 °C and incubated in DMEM containing 10% FBS, antibiotics and antimycotic in a single day. Cells had been filtered with a 70-µm cellphone strainer and cultured for experiments. Cells had been immortalized by using massive T-SV40 plasmid the use of XtremeGENE HP transfection reagent44.Oligo-DNAs
Sequence suggestions of all primer DNAs used in the study is provided in Supplementary desk 2.mobilephone lines
U2OS (ATCC HTB-96) and 293T (ATCC CRL-3216) have been maintained in DMEM supplemented with 10% FBS and antibiotics.Statistical evaluation
GraphPad Prism 7 was used to verify statistical magnitude. For RAD51 foci quantity in leptotene spermatocytes, immunofluorescence and metaphase spread experiments of siRNA-transfected cells, Mann–Whitney’s U-check and Tukey’s varied evaluation check was used. All p-values are proven in source file.Reporting abstract
extra counsel on experimental design is purchasable within the Nature analysis Reporting abstract linked to this article.
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Resells MS DPM for ‘near CDP’
At last month’s Storage Networking World Europe (SNW-E) trade show, Hewlett-Packard announced a slew of new data-protection and archiving products and services, many of which are based on products from OEM partners. Three of the more significant product announcements are in the data-protection category and two are in the archiving space.
The HP ProLiant DL 100 G2 and DL 380 G4 Data Protection Storage Server (DPSS) NAS appliances are powered by Microsoft’s System Center Data Protection Manager (DPM) and Windows Storage Server 2003 software. Microsoft’s DPM disk-based backup/recovery software is referred to as “near continuous data protection” (see “Microsoft enters D2D backup market,” InfoStor, August 2005, p. 1). HP claims that these disk-based backup/recovery platforms can reduce the risk of data loss by 96% and boost restore speeds by as much as 90% compared to traditional tape-based approaches.
Microsoft’s DPM competes with Veritas/Symantec’s recently released “Panther” CDP software (see “Symantec joins growing CDP field,” p. 1). DPM also competes to a degree with CDP products from vendors such as FalconStor, IBM (see “IBM delivers file-based CDP,” p. 1), InMage, Kashya, Lasso Logic, LiveVault, Mendocino Software, Mimosa Systems, Revivio, StoneFly Networks, Storactive, TimeSpring, and XOsoft.
Also at SNW-Europe, Hewlett-Packard introduced the StorageWorks 6840 Virtual Library System (VLS), which extends the capacity and performance of the HP 6000 VLS family.
The 6840 VLS provides a capacity of 40TB, compared to 10TB previously, and boosts performance by 40% to 575MBps. The VLS systems are virtual tape library (VTL) platforms, which emulate tape drives/libraries, based on technology from Sepaton.
HP also announced its Electronic Vaulting Services for Enterprises, which is based on Asigra’s Televaulting software and provides automated backup and vaulting to remote sites or HP data centers (vaults). The service is agent-less, but requires an appliance in the customer’s production environment that collects data based on user-defined policies. The vaulting service uses “single-instance store” technology to avoid duplication of data, and compresses and encrypts the data. Electronic Vaulting Services for Enterprises supports multi-vendor environments, as well as Windows, Linux, Unix, NetWare, and AS400 platforms.
HP’s StorageWorks File Migration Agent (FMA) allows users to move inactive data to a choice of cost-effective storage targets-including HP’s Reference Information Storage System (RISS), File System Extender (FSE), NAS, or tape devices-in a tiered storage infrastructure for information life-cycle management (ILM).
HP also announced the StorageWorks Reference Information Manager (RIM) for Database Archiving solution, which integrates OuterBay Technologies’ Application Data Management (ADM) database archiving software and uses ILM policies to automatically move database information to and from archived databases. Targeted databases include Oracle and SAP, but other databases are on the road map, too.
Other enhancements and upgrades designed to bolster HP’s data-protection and archiving portfolio include HP Enterprise Backup Solution (EBS), OpenView Storage Data Protector 5.5, StorageWorks Exchange 2003 Replication for HP EVA, StorageWorks Rapid Backup and Restore for the mySAP Business Suite, StorageWorks Replication Solutions Manager, and the Medical Archiving Solution.
Commenting on HP’s decision to launch a slew of products at once, instead of rolling them out one by one, Arun Taneja, consulting analyst and founder of the Taneja Group, says, “HP has lost momentum over the last two years to EMC and Network Appliance, and it needs to do something drastic to send a message that it’s back in the game. Announcing one or two products at a time won’t work.
“HP has been filling in many gaping holes in areas such as e-mail archiving,” Taneja continues. “It has a solid platform in RISS, which is now being presented more as a direct competitor to EMC’s Centera. For structured data, HP has the OuterBay solution, and it also has strong solutions for compliance. HP can now start competing effectively against IBM and EMC.”
Windows Home Server might say “home” in the product name, but its low maintenance cost makes it an ideal choice for small businesses. A simple, little WHS can provide comprehensive back up, remote access, and centralized storage for a workgroup. However, businesses don’t need all the fancy-pants media programs that come on HPs MediaSmart line. Enter the HP StorageWorks X510Data Vault.
Unfortunately the prices seem a bit off. These servers are housed in the same case use the same Windows Home Server software and seem to have the same hardware as the new MediaSmart line, but cost more for less storage. For instance, right now the MSRP of the new MediaSmart EX495 is $699 and comes with 1.5TB of storage along with a bunch of software that consolidates media and can share it on the Internet. But the HP StorageWorks X500 Data Vault comes with 1TB of storage for the same $699 price and all the extra software isn’t listed on the product page.
Marketing Windows Home Server to businesses makes a lot of sense, but overcharging them is just wrong. Maybe HP expects the models to be discounted sometime soon and a higher MSRP makes sales look even better.
HP (NYSE:HPQ) today introduced solutions to help small and midsize businesses (SMBs) improve data security, maximize productivity and minimize business risk while significantly reducing costs and energy use.
The new offerings expand the HP Total Care portfolio, which helps SMBs manage, protect and grow their businesses.
“By investing in new IT solutions now, SMBs will be in a stronger position to seize growth opportunities and thrive as the economy rebounds,” said Kathy Chou, vice president, Worldwide Small and Midsize Business Strategy, HP. “With today’s announcement, HP continues to enrich its Total Care offerings to meet the evolving needs of our SMB customers.”
“AMI has surveyed thousands of SMBs in over a dozen countries over the last four quarters, and noted that the current economy has greatly changed the way they purchase technology products and services,” said Anil Miglani, senior vice president, AMI-Partners. “As we exit the global recession, SMBs will try to protect their existing technology investments while making new investments to grow their business and strengthen customer relationships. HP is well-prepared to help SMB customers achieve this balanced growth through its comprehensive Total Care portfolio.”
Improve security and risk management
For SMBs needing increased levels of security to protect their data and keep mission-critical systems running smoothly, HP introduced these new solutions:
To significantly improve system availability while reducing the risk associated with security breaches and data, the
HP Total Care Business Risk Mitigation
solution offers customizable configurations of servers, storage, networking and security products. By leveraging this solution and best practices for data management, SMBs can reduce outages by as much as 85 percent.(1)
For affordable data management, the HP StorageWorks X500 Data Vault Series (starting at $699)(2) allows small businesses to remain competitive by improving the protection of critical business data and automating backups. It enables small businesses with up to 10 PC and Mac clients to store information in a central place and easily share files regardless of employee location. Also, business owners can save money through a low purchase price, which is up to 22 percent less than comparable solutions.(3)
For maximum uptime, the HP StorageWorks X3000 Network Storage Systems High Availability Bundles combine hardware and software into an efficient shared storage solution for file and application data. Based on the HP StorageWorks X3000 Network Storage Gateways and HP StorageWorks MSA2000 G2 storage arrays, the bundles increase efficiency by automatically eliminating duplicate files, protecting against drive failures and reducing setup time by up to 50 percent.(4) Helping to keep costs in check, the solution does not require extra license fees for networking protocols, file replication or snapshot capabilities.
Enhance productivity, reduce costs
To help customers save money, be more productive and manage security threats, HP announced:
Improved administrative productivity with the HP ProCurve 1810G Switch Series. This series provides affordable gigabit connectivity that can be configured and maintained without a large or specialized staff. It offer customers flexible deployment options such as a fan-less design for silent operation, mounting options for easy deployment in any location and network security capabilities for protection against denial-of-service attacks. The eight-port model also features a Power-over-Ethernet option for connectivity in locations without readily available power sources. The series also is supported by the ProCurve Lifetime Warranty(5) to help customers better manage their overall networking expenses by providing value and choice for their business applications.
For an affordable, lightweight notebook that does not compromise performance, the HP ProBook 5310m Notebook PC, starting at $699,(2) is the world’s thinnest full-performance notebook at 0.9-inches thin and 3.7 pounds. Ideal for mobile SMBs, it delivers seven hours of battery life,(6) sports a 13.3-inch diagonal LED high-definition display and a standard voltage processor. HP QuickWeb allows users to access the web in seconds when the notebook is shut down.(7)
Maximize impact, decrease energy use
For SMBs that want to affordably grow while minimizing their environmental impact, HP introduced new printing and online marketing solutions:
The HP Color LaserJet Professional CP5220 printer series, which is available for purchase in Asia and Europe, offers exceptional print quality and network performance, making it easy for small businesses to affordably market themselves. It is the first printer to offer HP Auto-Off Technology, an industry-leading technology that intelligently senses when there is no print activity and automatically adjusts the power settings. This latest addition to the HP LaserJet family builds on 25 years of leadership in innovation, quality, performance and dependability, and sets the gold standard in business printing.
To help SMBs easily select the best HP LaserJet printing system for their business, HP announced new sub-branding. Customers can choose from a comprehensive line of HP LaserJet “Professional” printers that provide professional and cost-effective results, while larger organizations can select from the HP LaserJet “Enterprise” portfolio.
To help small businesses better connect with their customers, HP released a new version of its MarketSplash by HP web service. HP printer and PC customers in the United States can now download and edit hundreds of professional-quality brochure, flyer and business card templates at no charge and print them in-house. Beginning next month, MarketSplash will offer a print fulfillment option that enables customers to select a local print service provider.
HP and Yahoo! have teamed to help small businesses in the United States easily and affordably create a cohesive brand identity across different online and offline marketing functions. Through the HP Creative Studio, the HP Total Care site and the Yahoo! Small Business portal, customers can receive special offers including web hosting prices for as low as $7.46 a month(2) and access custom design services from Logoworks by HP to create a professional-looking website.
New services and financing offers
To complement its new solutions, HP introduced services and financing offers to help SMBs in the United States purchase, use and manage their IT resources:
To help SMBs manage costs and make purchasing easy, HP offers flexible financing solutions to deploy next-generation HP technology and services through HP Financial Services, the company’s leasing and lifecycle asset management services subsidiary. From now through Oct. 31, 2009, SMBs can take advantage of the Economic Recovery Lease program, which offers a 36-month plan with fixed price purchase options.
From now until Dec. 31, 2009, SMBs can receive up to $1,000 cash back when purchasing a new HP LaserJet, Officejet Pro or Scanjet and recycling an old printer through the HP Trade-in and Save Program. Within the last six months, HP has generated nearly $16 million in revenue and sold more than 17,000 units through the program.
New channel offerings
Lastly, HP announced enhanced SMB offerings available through its channel partners, including channel-only products, channel-led Managed Print Services programs and HP certified solutions, that enable SMBs to better compete in today’s marketplace. The offerings include:
Products available through the channel will initially focus on the workflow, imaging and printing security and job accounting, and device management arenas;
Greater investment in tools and programs that enable reseller partners to offer Managed Print Services to their customers. In the United States, HP has established new relationships with industry leaders that offer managed print infrastructure and services for resale by value-added reseller partners. In Europe, HP is creating an integrated platform and brokering a network of service partners that will enable resellers to sell contractual print offerings as well as higher valued services not previously available to SMB customers; and
Certified solutions for the channel that include partner training, product sourcing and technical support for select independent software vendor solutions from HP’s Solutions Business Partner Program.
Additional information about HP’s expanded Total Care offering for SMBs is available at
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